Methadone is contraindicated hinein patients with a known hypersensitivity to methadone hydrochloride or any other ingredient hinein methadone hydrochloride tablets.
Take methadone hydrochloride tablets exactly as prescribed. Follow your doctor's directions exactly. Your doctor may change your dose based on your reactions to the medicine.
Don’t put this medication hinein your car’s glove compartment or leave it rein the car. Be sure to avoid doing this when the weather is very hot or very cold.
Opioide sind sowohl körpereigene denn selbst natürliche sowie synthetisch hergestellte Substanzen die an den Opioidrezeptoren wirken. Es handelt zigeunern dabei um eine morphinartige Betätigung, die geradewegs zur Sucht fluorühren kann.
Particular vigilance is necessary during treatment initiation, during conversion from one opioid to another, and during dose titration.
Although antiretroviral drugs such as efavirenz, nelfinavir, nevirapine, ritonavir, lopinavir + ritonavir combination are known to inhibit some CYPs, they are shown to reduce the plasma levels of methadone, possibly due to their CYP induction activity. Therefore, drugs administered concomitantly with methadone should be evaluated for interaction potential; clinicians are advised to evaluate individual response to drug therapy before making a dosage adjustment.
Pregnancy and neonatal opioid withdrawal syndrome warning: Children who are born to mothers Weltgesundheitsorganisation used this drug for a long time during pregnancy are at risk of neonatal withdrawal syndrome. This can be life threatening to the child.
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Zensur – Equianalgesic methadone dosing varies not only between patients, but also within the same patient, depending on baseline morphine (or other opioid) dose. Table 1 has been included in order to illustrate this concept and to provide a safe starting point for opioid conversion. Methadone dosing should not Beryllium based solely on these tables. Methadone conversion and dose titration methods should always be individualized to account for the patient's prior opioid exposure, general medical condition, concomitant medication, and anticipated breakthrough medication use.
for maintenance treatment of narcotic drug addiction along with other social and medical services. Stopping maintenance treatment of narcotic drug addiction with methadone hydrochloride tablets may result hinein a return to narcotic drug use.
The safety and effectiveness of this drug hasn’t been established hinein children. It shouldn’t Beryllium used in children younger than 18 years.
Dosage adjustment using higher doses or administering the daily dose in divided doses may be necessary rein pregnant women treated with methadone (Weiher CLINICAL PHARMACOLOGY and DOSAGE AND ADMINISTRATION).
For people with breathing problems: This drug can cause breathing problems. It can also worsen breathing problems you already have.
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